Prilocaine Hydrochloride Prilocaine Free Base USP Crystalline Powder
Prilocaine Hydrochloride | Prilocaine USP
Prilocaine Hcl
Name: Prilocaine Hydrochloride
CAS No: 1786-81-8
Molecular Formula: C13H21ClN2O
Molecular Weight: 256.77
EINECS No: 217-244-0
Appearance: White Solid
Melting point: 168-170°C
Use: Prilocaine is a local anesthetic of the amino amide type. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a topical preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia .
Prilocaine Hydrochloride USP Pharm Materials Chemical Test Specification (COA) :
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Product name
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Prilocaine hydrochloride
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CAS
CAS No.
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1786-81-8
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Outer Packing
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25kg
25kg
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Production date
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2016.03.11
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Shelf life
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2018.03.10
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Standard adopted
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USP36
USP36
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Items of analysis
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Specification
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Results
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Description
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White crystalline powder
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Complies
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Solubility
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,,,
Freely soluble in water and in alcohol ,slightly soluble in chloroform,very slightly soluble in acetone; practically insoluble in ether
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Complies
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Identification
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By IR absorption,To match with working standard
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Complies
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Identification
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Should be positive response
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Complies
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Identification
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Should display the reaction of chloride differentiated
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Complies
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Melting Point
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166~169ºC
166~169ºC
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166~168ºC
166~168ºC
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Loss on drying
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≤ 0.3%
≤ 0.3%
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0.13%
0.13%
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Residue on ignition
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≤0.1%
≤0.1%
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0.03%
0.03%
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Heavy metals
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≤0.002%
≤0.002%
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<0.002%
<0.002%
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Residual solvents
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Should be to match with the standard
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Complies
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Assay
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99.0% ~101.0%()
99.0% ~101.0%(on the anhydrous basis )
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99.46%
99.46%
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Conclusion
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Qualified
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