Adrafinil Crl-40028 Olmifon API Excitant Chemical Prodrug of Modafinil
Adrafinil Pure Powder 99.42%
Product Name: Adrafinil
Also Known as: Olmifon, CRL-40028, Prodrug of Modafini
CAS: 63547-13-7
MF: C15H15NO3S
MW: 289.35
EINECS: 264-303-1
Appearance: Pink to off-white crystalline powder
Melting point : 149.0~149.3 °C
Assay(HPLC) : 99.42%
Adrafinil (brand name Olmifon) is a discontinued wakefulness-promoting agent (or eugeroic) that was formerly used in France to promote vigilance (alertness), attention, wakefulness, mood, and other parameters, particularly in the elderly. It was also used off-label by individuals who wished to avoid fatigue, such as night workers or others who needed to stay awake and alert for long periods of time. Additionally, “adrafinil is known to a larger nonscientific audience, where it is considered to be a nootropic agent.”
Adrafinil is a prodrug; it is primarily metabolized in vivo to modafinil, resulting in very similar pharmacological effects. Unlike modafinil, however, it takes time for the etabolite to accumulate to active levels in the bloodstream. Effects usually are apparent within 45-60 minutes when taken orally on an empty stomach.
Adrafinil Olmifon Pharma Materials Chemical Tests (COA) :
|
Product name
|
Adrafinil
|
|
CAS
CAS No.
|
63547-13-7
|
Outer Packing
|
1KG
|
|
Production date
|
Dec. 17 th ,2016
|
Shelf life
|
Dec. 16 th ,2019
|
|
Standard adopted
|
in-house standard
|
|
Items of analysis
|
Specification
|
Results
|
|
Appearance
|
Pink to off-white crystalline powder
|
Conform
|
|
Solubility
|
Soluble in methanol, slightly soluble in ethyl acetate and methylene hloride, practically insoluble in water
|
Conform
|
|
Melting point
|
148ºC~150ºC
|
149.0~149.3ºC
|
|
Identification
|
IR /HPLC
|
Conform
|
|
Loss on drying
|
≤0.5%
|
0.32%
|
|
Isomer
|
≤1.0%max
|
0.66%
|
|
Other Max Single impurity
|
<0.1%
|
0.08%
|
|
Residue on ignition
|
≤0.1%
|
0.078%
|
|
Heavy metal
|
≤20ppm
|
Conform
|
|
Assay(HPLC)
|
98%~102%
|
99.42%
|
|
Conclusion
|
Qualified
|
