Tretinoin USP36 Accutane Clear Acne RETINOIC ACID Chemical Isotretinoin
Product Name: Tretinoin
Other names: TRETINOIN, TRANS-RETINOIC ACID, VITAMIN A ACID, RETINOIC ACID.
CAS: 302-79-4
MF: C20H28O2
MW: 300.44
EINECS: 206-129-0
Product Categories: PHARMACEUTICALS;Active Pharmaceutical Ingredients;APIs;Biochemistry;Terpenes;Terpenes (Others);Vitamins;Intermediates & Fine Chemicals;Retinoids;Intracellular receptor;API;intermediates;Inhibitors.
Chemical Properties: Yellow to light-orange crystalline powder.
Melting Point: 180-181 °C(lit.)
Water Solubility : insoluble
Sensitive : Light Sensitive
Uses: Tretinoin is commonly used in dermatology drugs, which is the department of vitamin A (Victoria methanol) metabolic intermediates.It mainly affects the growth of bones and epithelial metabolism, can promote epithelial cell proliferation and updates, and can inhibit the proliferation and differentiation of keratinocytes, so hyperkeratosis can be back to normal.
Tretinoin USP36 Active Pharma Ingredient
USP36 Tretinoin (RETINOIC ACID) powder Chemical Test Specifications (COA):
|
Product name
|
A()
Tretinoin
|
|
CAS
CAS No.
|
302-79-4
|
Outer Packing
|
100G
100G
|
|
Production date
|
2017.07.05
|
Shelf life
|
2022.07.04
|
|
Standard adopted
|
USP 36
|
|
Items of analysis
|
Specification
|
Results
|
|
Appearance
|
Yellow to light-orange crystalline powder
|
Yellow crystalline powder
|
|
Identification
|
1.The IR absorption spectrum should correspond with reference spectrum 2.Should exhibits maximum absorption at 352nm
|
1.Correspond with reference spectrum 2.Exhibits Maximum absorption at 352nm
|
|
Loss on drying
|
≤0.5%
|
0.3%
|
|
Residue on ignition
|
≤0.1%
|
0.03%
|
|
Heavy metals
|
≤0.002%
|
<0.002%
|
|
Isotretinoin
|
≤5.0%
|
0.1%
|
|
Related Substances
|
≤0.5%
|
0.26%
|
|
Assay (anhydrous)
|
97.0%-103.0%
|
99.8%
|
|
Methanol
|
≤3000 ppm
|
20ppm
|
|
≤ 5000 ppm
|
3000ppm
|
|
≤ 5000 ppm
|
17 ppm
|
|
Conclusion
|
Qualified
|
