L-Epinephrine USP37 API Bronchodilator Adrenaline Manufacturer
L-Epinephrine
L-Epinephrine
Other name: L(-)-Epinephrine, Adrenaline , Epinephrine, L-adrenaline
MF: C9H13NO3
MW: 183.2
EINECS: 200-098-7
Melting point: 215 °C
Sensitive : Air & Light Sensitive
Stability: Stable. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents. Light sensitive.
Chemical Properties: off-white powder.
L-Epinephrine Uses: L-Adrenaline (Epinephrine) belongs to a group of the compounds known as catecholamines, which play an important role in the regulation of physiological process in living organisms. Endogenous catcholamine with combined α-and β-agonist activity. Principal sympathomimetic hormone produced by the adrenal medulla. Bronchodilator; cardiostimulant; mydriatic; antiglaucoma.
USP37 L-Epinephrine powder Chemical Test Specifications (COA):
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Product name
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L-Epinephrine
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CAS
CAS No.
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51-43-4
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Outer Packing
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500g/
500G/BAG
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Production date
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Nov.15.2015
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Shelf life
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Nov.14.2017
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Standard adopted
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USP37
USP37
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Items of analysis
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Specification
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Results
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Characters
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White or greyish-white crystalline odorless powder
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Off-white crystalline odorless power
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Identification
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0.10 n:
0.10N iodine: deep red color
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Validity
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Solubility
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very slightly soluble in water and in alcohol, insoluble in ether, in chloroform, and in fixed and volatile oils.
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PASS
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Specific rotaion
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-50.0°~ -53.5°
Between -50.0° and -53.5°
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-52.2°
-52.2°
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Loss on drying
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≤2.0%
not more than 2.0%
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0.3%
0.3%
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Sulphated Ash
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≤0.1%
not more than 0.1%
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0.01%
0.01%
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Limit of adrenalone
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310nm≤0.20
at 310 nm not more than 0.20
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0.005
0.005
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Linit of noreponephrine
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≤2.0%
not more than 2.0%
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0.0%
0.0%
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Assay
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97.0%~102.0%
Not less than 97.0% and not more than 102.0%
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99.6%
99.6%
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Residula solvents
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≤3000ppm
Methanol: not more than 3000ppm
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=800ppm
Methanol:800ppm
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Storage
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Store in vacuum and protected from light
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Store in vacuum and protected from light
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Conclusion
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Qualified
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