PHENIBUT Noofen Citrocard Anti-angst Chemisch antidepressivum Slapeloosheid Kalmerende medicijnen
PHENIBUT
Other Names: 4-Amino-3-phenylbutyric acid hydrochloride, Phenibut, Noofen, Citrocard
CAS: 1078-21-3
MF: C10H14ClNO2
Mw: 215.68
EINECS: 214-079-6
Verschijning: white crystalline powder.
PHENIBUT pure substance
Uses: PHENIBUT is a sedative, Has a calming effect, reduce tension, spanning, improve sleep; prolong and strengthen hypnosis, anesthesia, antipsychotics.
Phenibut, sold under the brand names Noofen and Citrocard, is a central depressant which is used in Russia for a variety of indications. It has also been reported by some researchers to possess nootropic effects due to its ability to improve neurological functions, medical citation needed] but others have not observed these effects. It is generally accepted that phenibut has anxiolytic effects in both animal models and in humans.
Phenibut is chemically related to the neurotransmitter γ-aminobutyric acid (GABA). It is believed to act as a selective GABAB receptor agonist, similarly to baclofen; studies are conflicting as to whether phenibut also acts as a GABAA receptor agonist. More recently, phenibut has been found to act preferentially as a blocker of α2δ subunit-containing voltage-gated calcium channels, similarly to gabapentin and pregabalin. As such, by definition, phenibut is a gabapentinoid.
Phenibut Medical uses
Phenibut is used in Russia as a pharmaceutical drug to treat a wide range of ailments, including anxiety, depression, asthenia, insomnia, alcoholism, posttraumatic stress disorder, stuttering, and vestibular disorders, among other conditions. In many other parts of the world, phenibut is not approved for clinical use, and is instead sold as a nutritional supplement.
