Rimonabant chemical
Rimonabant SR141716 Weight Loss Pharma Chemical ACOMPLIA
Rimonabant (SR141716)
Synonyms: ACOMPLIA;RIMONABANT;RIMONABANT(ACOMPLIA,SR141716);5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidinopyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-;5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide
CAS: 168273-06-1
MF: C22H21Cl3N4O
MW: 463.79
Rimonabant hydrochloride
MF: C22H21Cl3N4O.ClH
MW: 500.25
CAS: 158681-13-1
Rimonabant (also known as SR141716; trade names Acomplia, Zimulti) was an anorectic antiobesity drug. Rimonabant is an inverse agonist for the cannabinoid receptor CB1 and was the first drug approved in that class. Rimonabant is a diet pills developed by the French company Sanofi-Aventis and the first cannabinoid type 1 receptor (CB1) antagonist for obesity treatment by selectively blocking marijuana in the EC system (Cannabinoid-1, CB1) receptors, can significantly reduce body weight, reduce waist circumference, reduce cardiovascular disease and other risk factors, but also can improve blood lipids and insulin resistance and metabolic syndrome, especially for There is a risk of clinical obesity or heart disease.
Rimonabant Pharma materials Chemical Test Specifications (COA):
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Product Name
Product name
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Rimonabant
Rimonabant
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CAS
CAS No.
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168273-06-1
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Packing
Outer Packing
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MFG
Production date
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May 14th. 2015
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EXPIRY DATE
Shelf life
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May 13th. 2017
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Products Standard
Standard adopted
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Enterprise Standard
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Analysis Item
Items of analysis
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Quality Standard
Specification
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Results
Results
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Assay by (HPLC)
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99%-101%
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99.43%
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Characters/appearance
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White to off White powder
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Complies
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Odor and taste
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Odorless
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Complies
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Identification
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Positive reaction
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Complies
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Mesh size/sieve analysis
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100% pass 80 mesh
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Complies
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Loss on drying
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1% Max
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0.78%
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Water
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≤2.0%
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0.1%
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Residue on ignition
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01%Max
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Complies
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Single impurity
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0.1% Max
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Complies
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Malting point
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272.25 ºC
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Complies
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Bolling point
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627 .69 ºC
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Complies
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Refractive Index
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N20O1.67
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Complies
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PH
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50-7.0
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6.5
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pK Values
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pK. 11.31(Predicted). pK„ 3. 22 (Predicted)
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Complies
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Solubility
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Soluble in ethanol (-20 mg/ml). DMSO (25 mg/ml) .DMF (-20mg/ml). and water (< 1 mg/ml)
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Complies
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Heavy Metals
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NMT 10ppm
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Complies
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Microbiological Control
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78cfu/g
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78cfu/g
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Total Plate Count
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1000 cfu/g Max
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Negative
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Fungi
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<100/g
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Negative
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Salmonella
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Negative
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Negative
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Coll
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negative
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negative
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Conclusion
Conclusion
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Qualified
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