Rimonabant chemical
Rimonabant SR141716 Perte de poids Pharma Chemical ACOMPLIA
Rimonabant (SR141716)
Synonymes: ACCOMPLIR;RIMONABANT;RIMONABANT(ACCOMPLIR,SR141716);5-(4-Chlorophényle)-1-(2,4-dichlorophényle)-4-méthyl-N-pipéridinopyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide, 5-(4-chlorophényle)-1-(2,4-dichlorophényle)-4-méthyl-N-1-pipéridinyl-;5-(4-Chlorophényle)-1-(2,4-dichlorophényle)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide
CAS: 168273-06-1
MF: C22H21Cl3N4O
MW: 463.79
Rimonabant hydrochloride
MF: C22H21Cl3N4O.ClH
MW: 500.25
CAS: 158681-13-1
Rimonabant (également connu sous le nom de SR141716; noms commerciaux Acomplia, Zimulti) était un médicament anti-obésité anorexigène. Le rimonabant est un agoniste inverse du récepteur cannabinoïde CB1 et a été le premier médicament approuvé dans cette classe.. Rimonabant is a diet pills developed by the French company Sanofi-Aventis and the first cannabinoid type 1 receptor (CB1) antagonist for obesity treatment by selectively blocking marijuana in the EC system (Cannabinoid-1, CB1) receptors, can significantly reduce body weight, reduce waist circumference, reduce cardiovascular disease and other risk factors, but also can improve blood lipids and insulin resistance and metabolic syndrome, especially for There is a risk of clinical obesity or heart disease.
Rimonabant Pharma materials Chemical Test Specifications (COA):
Nom du produit
Product name
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Rimonabant
Rimonabant
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CAS
n ° CAS.
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168273-06-1
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Emballage
Outer Packing
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|
MFG
Date de production
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May 14th. 2015
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EXPIRY DATE
Durée de conservation
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May 13th. 2017
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Products Standard
Norme adoptée
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Norme d'entreprise
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Analysis Item
Éléments d'analyse
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Qualité standard
spécification
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Résultats
Résultats
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Assay by (CLHP)
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99%-101%
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99.43%
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Characters/appearance
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White to off White powder
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Complies
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Odor and taste
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Odorless
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Complies
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Identification
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Positive reaction
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Complies
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Mesh size/sieve analysis
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100% pass 80 mesh
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Complies
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Perte au séchage
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1% Max
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0.78%
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Water
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≤2.0%
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0.1%
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Residue on ignition
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01%Max
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Complies
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Single impurity
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0.1% Max
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Complies
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Malting point
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272.25 ºC
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Complies
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Bolling point
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627 .69 ºC
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Complies
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Refractive Index
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N20O1.67
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Complies
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PH
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50-7.0
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6.5
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pK Values
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pK. 11.31(Predicted). pK„ 3. 22 (Predicted)
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Complies
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Solubility
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Soluble in ethanol (-20 mg/ml). DMSO (25 mg/ml) .DMF (-20mg/ml). and water (< 1 mg/ml)
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Complies
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Heavy Metals
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NMT 10ppm
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Complies
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Microbiological Control
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78cfu/g
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78cfu/g
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Total Plate Count
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1000 cfu/g Max
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Negative
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Fungi
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<100/g
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Negative
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Salmonella
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Negative
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Negative
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Coll
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negative
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negative
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Conclusion
Conclusion
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Qualifié
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